製品: B3GALTL Antibody
カタログ: DF3835
タンパク質の説明: Rabbit polyclonal antibody to B3GALTL
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Dog
分子量: 57 KD; 57kD(Calculated).
ユニプロット: Q6Y288
RRID: AB_2836192

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Dog(91%)
クローナリティ:
Polyclonal
特異性:
B3GALTL Antibody detects endogenous levels of total B3GALTL.
RRID:
AB_2836192
引用形式: Affinity Biosciences Cat# DF3835, RRID:AB_2836192.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B3GlcT; B3GTL; Beta 1,3 galactosyltransferase like; Beta 3 galactosyltransferase like; Beta-1,3-glucosyltransferase; Beta-3-glycosyltransferase-like; Beta3Glc-T; Beta3GlcT; Galactosyltransferase; GalT;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q6Y288 B3GLT_HUMAN:

Widely expressed, with highest levels in testis and uterus.

タンパク質配列:
MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTVFKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQHLLSCYDSGEPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQVPISFHKHWNIDPVKVYFTWLAPSDEDKARQETQKGFREEL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
91
Horse
73
Rabbit
64
Bovine
45
Sheep
36
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6Y288 基板として

Site PTM Type Enzyme
K72 Ubiquitination
S357 Phosphorylation
S481 Phosphorylation

研究背景

機能:

O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.

細胞の位置付け:

Endoplasmic reticulum membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed, with highest levels in testis and uterus.

タンパク質ファミリー:

Belongs to the glycosyltransferase 31 family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > Other types of O-glycan biosynthesis.

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