BAIAP2L2 Antibody - #DF3854
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3854, RRID:AB_2836211.
折りたたみ／展開
BAI1-associated protein 2-like 2; BAI1-associated protein 2-like protein 2; baiap2l2; BAIAP2L2 BAI1-associated protein 2-like 2; BC048937; BI2L2_HUMAN; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; FLJ22582; Pinkbar; Planar intestinal- and kidney-specific BAR domain protein; RP5-1039K5.3;
免疫原
- Q6UXY1 BI2L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPEMDQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQSPTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELEYRHRAANLEKCMSELWRMERKRDKNVREMKESVNRLHAQMQAFVSESQRAAELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQSEASRSPSRAHSPGLLGPALGPPYPSGRLTPTCLDMPPRPLGEFSSPRSRHGSGSYGTEPDARPASQLEPDRRSLPRTPSASSLYSGSAQSSRSNSFGERPGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGWFPEAYVKALEEGPVNPMTPVTPMTSMTSMSPMTPMNPGNELPSRSYPLRGSHSLDDLLDRPGNSIAPSEYWDGQSRSRTPSRVPSRAPSPAPPPLPSSRRSSMGSTAVATDVKKLMSSEQYPPQELFPRGTNPFATVKLRPTITNDRSAPLIR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6UXY1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S231 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| T297 | Phosphorylation | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| Y304 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| S453 | Phosphorylation | Uniprot | |
| T455 | Phosphorylation | Uniprot | |
| S457 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| S465 | Phosphorylation | Uniprot | |
| S477 | Phosphorylation | Uniprot | |
| S478 | Phosphorylation | Uniprot | |
| T512 | Phosphorylation | Uniprot |
研究背景
Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity).
Cell membrane>Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane.
Note: Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.
Expressed in the epithelial layer of the intestine (at protein level).
The IMD domain consisting of an antiparallel dimer of three-helix bundles, featuring on one side a positively charged. The N-terminal alpha-helix inserts into the lipid bilayer. Also forms homodimers and homooligomers. The residue Trp-141 is essential for oligomer formation (By similarity).
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.