Calcipressin 1 Antibody - #DF3861
| 製品: | Calcipressin 1 Antibody |
| カタログ: | DF3861 |
| タンパク質の説明: | Rabbit polyclonal antibody to Calcipressin 1 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 22 KD; 28kD(Calculated). |
| ユニプロット: | P53805 |
| RRID: | AB_2836218 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3861, RRID:AB_2836218.
折りたたみ／展開
Adapt 78; Adapt78; Calcipressin 1; Calcipressin-1; Calcium and oxidant inducible mRNA; CSP 1; CSP1; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; DSC 1; DSC1; DSCR 1; DSCR1; MCIP 1; MCIP1; Modulatory calcineurin interacting protein 1; Myocyte enriched calcineurin interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; Near DSCR proline rich protein; RCAN1; RCAN1_HUMAN; RCN 1; RCN1; Regulator of calcineurin 1;
免疫原
Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.
- P53805 RCAN1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEDGVAGPQLGAAAEAAEAAEARARPGVTLRPFAPLSGAAEADEGGGDWSFIDCEMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P53805 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K86 | Ubiquitination | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| T129 | Phosphorylation | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| S163 | Phosphorylation | Q99759 (MAP3K3) , P49841 (GSK3B) | Uniprot |
| S167 | Phosphorylation | Q99759 (MAP3K3) , Q13627 (DYRK1A) , P27361 (MAPK3) , P28482 (MAPK1) | Uniprot |
| T179 | Phosphorylation | Uniprot | |
| Y188 | Phosphorylation | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| T208 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| T241 | Phosphorylation | Uniprot | |
| T247 | Phosphorylation | Q13627 (DYRK1A) | Uniprot |
研究背景
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Phosphorylation increases its ability to inhibit calcineurin and decreases protein half-life.
Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.
Interacts with RAF1. Interacts with PPP3CA and PPP3R1.
Belongs to the RCAN family.
研究領域
· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway. (View pathway)
· Organismal Systems > Endocrine system > Oxytocin signaling pathway.
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