CHST10 Antibody - #DF3881
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3881, RRID:AB_2836234.
折りたたみ／展開
Carbohydrate sulfotransferase 10; CHST10; CHSTA_HUMAN; EC 2.8.2.-; HNK-1 sulfotransferase; HNK-1ST; HNK1ST; huHNK-1ST; MGC17148; OTTHUMP00000203188;
免疫原
In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.
- O43529 CHSTA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDVYSAKQEFLFLTTMPEVRKLPEEKHIPEELKPTGKELPDSQLVQPLVYMERLELIRNVCRDDALKNLSHTPVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSDAEIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRRNRTETRGIQFEDFVRYLGDPNHRWLDLQFGDHIIHWVTYVELCAPCEIMYSVIGHHETLEDDAPYILKEAGIDHLVSYPTIPPGITVYNRTKVEHYFLGISKRDIRRLYARFEGDFKLFGYQKPDFLLN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43529 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T66 | O-Glycosylation | Uniprot | |
| T66 | Phosphorylation | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| K98 | Ubiquitination | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| S328 | Phosphorylation | Uniprot | |
| K350 | Ubiquitination | Uniprot |
研究背景
Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
Golgi apparatus membrane>Single-pass type II membrane protein.
In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.
Belongs to the sulfotransferase 2 family.
研究領域
· Metabolism > Global and overview maps > Metabolic pathways.
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