製品: CSTF2T Antibody
カタログ: DF3948
タンパク質の説明: Rabbit polyclonal antibody to CSTF2T
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Dog
分子量: 64 KD; 64kD(Calculated).
ユニプロット: Q9H0L4
RRID: AB_2836301

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
CSTF2T Antibody detects endogenous levels of total CSTF2T.
RRID:
AB_2836301
引用形式: Affinity Biosciences Cat# DF3948, RRID:AB_2836301.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CF 1 64 kDa subunit tau; CF-1 64 kDa subunit tau variant; CF1 64 kDa subunit, tau variant; Cleavage stimulation factor 3' pre RNA, subunit 2 64kDa tau variant; Cleavage stimulation factor 64 kDa subunit tau; Cleavage stimulation factor 64 kDa subunit tau variant; Cleavage stimulation factor 64 kDa subunit, tau variant; Cleavage stimulation factor subunit 2 tau; Cleavage stimulation factor subunit 2 tau variant; CSTF 64 kDa subunit tau; CSTF 64 kDa subunit tau variant; CSTF 64 kDa subunit, tau variant; CstF 64T; CSTF2T; CSTF2T f; CSTFT_HUMAN; KIAA0689; TauCstF-64; TauCstF64;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H0L4 基板として

Site PTM Type Enzyme
S2 Phosphorylation
S3 Phosphorylation
K96 Ubiquitination
S113 Phosphorylation
K145 Ubiquitination
K148 Ubiquitination
K189 Ubiquitination
K194 Ubiquitination
T198 Phosphorylation
S205 Phosphorylation
S279 Phosphorylation
R311 Methylation
R316 Methylation
T320 Phosphorylation
R327 Methylation
R338 Methylation
T341 Phosphorylation
S344 Phosphorylation
T346 Phosphorylation
R352 Methylation
S368 Phosphorylation
R373 Methylation
R381 Methylation
R389 Methylation
R396 Methylation
R403 Methylation
R410 Methylation
R413 Methylation
C441 S-Nitrosylation
R461 Methylation
S466 Phosphorylation
S467 Phosphorylation
T472 Phosphorylation
S557 Phosphorylation
S561 Phosphorylation
S563 Phosphorylation
S567 Phosphorylation
T570 Phosphorylation
S601 Phosphorylation
K606 Ubiquitination
K611 Ubiquitination

研究背景

機能:

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

研究領域

· Genetic Information Processing > Translation > mRNA surveillance pathway.

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