CNTN2 Antibody - #DF3969
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3969, RRID:AB_2836322.
折りたたみ／展開
Axonal glycoprotein TAG 1; Axonal glycoprotein TAG-1; Axonal glycoprotein TAG1; Axonin 1; Axonin-1; Axonin1; AXT; CNTN 2; Cntn2; CNTN2_HUMAN; contactin 2 (axonal); Contactin 2; Contactin-2; Contactin2; DKFZp781D102; MGC157722; TAG 1; TAG 564; TAG564; TAX 1; TAX; TAX-1; TAX1; Transient axonal glycoprotein 1; Transiently expressed axonal glycoprotein;
免疫原
- Q02246 CNTN2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTATRRKPHLLLVAAVALVSSSAWSSALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQDMNGILLGYEIRYWKAGDKEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQNDLHLTPTLHLTGKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAEVHIVRNGGTSMMVENMAVRPAPHPGTVISHSVAMLILIGSLEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02246 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y71 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| Y205 | Phosphorylation | Uniprot | |
| T210 | Phosphorylation | Uniprot | |
| S462 | Phosphorylation | Uniprot | |
| T647 | Phosphorylation | Uniprot | |
| T887 | Phosphorylation | Uniprot | |
| Y891 | Phosphorylation | Uniprot | |
| N904 | N-Glycosylation | Uniprot | |
| T986 | Phosphorylation | Uniprot | |
| T987 | Phosphorylation | Uniprot |
研究背景
In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion.
Cell membrane>Lipid-anchor.
Note: Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
Belongs to the immunoglobulin superfamily. Contactin family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.