DSG2 Antibody - #DF3988
(5)
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse
予測:
Pig(82%), Horse(82%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
DSG2 Antibody detects endogenous levels of total DSG2.
RRID:
AB_2836348
引用形式: Affinity Biosciences Cat# DF3988, RRID:AB_2836348.
引用形式: Affinity Biosciences Cat# DF3988, RRID:AB_2836348.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
ARVC 10; ARVC10; ARVD 10; ARVD10; Cadherin family member 5; CDHF 5; CDHF5; CMD1BB; Desmoglein 2; Desmoglein-2; Desmoglein2; DSG 2; DSG2; DSG2_HUMAN; HDGC; HDGC included; Human Desmoglein colon; MGC117034; MGC117036; MGC117037;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質配列:
- Q14126 DSG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
82
Horse
82
Dog
82
Bovine
73
Sheep
73
Rabbit
64
Xenopus
60
Chicken
55
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14126 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| R81 | Methylation | Uniprot | |
| N112 | N-Glycosylation | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| N182 | N-Glycosylation | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| Y212 | Phosphorylation | Uniprot | |
| Y221 | Phosphorylation | Uniprot | |
| Y235 | Phosphorylation | Uniprot | |
| T291 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| R434 | Methylation | Uniprot | |
| N462 | N-Glycosylation | Uniprot | |
| T484 | Phosphorylation | Uniprot | |
| S551 | Phosphorylation | Uniprot | |
| T552 | Phosphorylation | Uniprot | |
| S559 | Phosphorylation | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| T645 | Phosphorylation | Uniprot | |
| T650 | Phosphorylation | Uniprot | |
| K667 | Ubiquitination | Uniprot | |
| S680 | Phosphorylation | Uniprot | |
| T695 | Phosphorylation | Uniprot | |
| K697 | Methylation | Uniprot | |
| K697 | Ubiquitination | Uniprot | |
| S699 | Phosphorylation | Uniprot | |
| S700 | Phosphorylation | Uniprot | |
| S701 | Phosphorylation | Uniprot | |
| S703 | Phosphorylation | Uniprot | |
| K706 | Ubiquitination | Uniprot | |
| S712 | Phosphorylation | Uniprot | |
| S723 | Phosphorylation | Uniprot | |
| S726 | Phosphorylation | Uniprot | |
| T733 | Phosphorylation | Uniprot | |
| T744 | Phosphorylation | Uniprot | |
| T745 | Phosphorylation | Uniprot | |
| K746 | Ubiquitination | Uniprot | |
| R773 | Methylation | Uniprot | |
| Y775 | Phosphorylation | Uniprot | |
| K779 | Ubiquitination | Uniprot | |
| S782 | Phosphorylation | Uniprot | |
| Y783 | Phosphorylation | Uniprot | |
| T791 | Phosphorylation | Uniprot | |
| T804 | Phosphorylation | Uniprot | |
| S806 | Phosphorylation | Uniprot | |
| S810 | Phosphorylation | Uniprot | |
| S815 | Phosphorylation | Uniprot | |
| K832 | Ubiquitination | Uniprot | |
| T835 | Phosphorylation | Uniprot | |
| K849 | Ubiquitination | Uniprot | |
| T874 | Phosphorylation | Uniprot | |
| T881 | Phosphorylation | Uniprot | |
| Y882 | Phosphorylation | Uniprot | |
| S884 | Phosphorylation | Uniprot | |
| S893 | Phosphorylation | Uniprot | |
| K901 | Ubiquitination | Uniprot | |
| T903 | Phosphorylation | Uniprot | |
| S911 | Phosphorylation | Uniprot | |
| T922 | Phosphorylation | Uniprot | |
| S939 | Phosphorylation | Uniprot | |
| T942 | Phosphorylation | Uniprot | |
| Y968 | Phosphorylation | Uniprot | |
| T973 | Phosphorylation | Uniprot | |
| Y979 | Phosphorylation | Uniprot | |
| T984 | Phosphorylation | Uniprot | |
| S999 | Phosphorylation | Uniprot | |
| Y1013 | Phosphorylation | Uniprot | |
| S1021 | Phosphorylation | Uniprot | |
| S1055 | Phosphorylation | Uniprot | |
| T1056 | Phosphorylation | Uniprot | |
| S1059 | Phosphorylation | Uniprot | |
| S1060 | Phosphorylation | Uniprot | |
| Y1061 | Phosphorylation | Uniprot | |
| S1093 | Phosphorylation | Uniprot | |
| S1098 | Phosphorylation | Uniprot | |
| T1099 | Phosphorylation | Uniprot | |
| K1109 | Ubiquitination | Uniprot | |
| S1111 | Phosphorylation | Uniprot | |
| Y1117 | Phosphorylation | Uniprot | |
| S1118 | Phosphorylation | Uniprot |
研究背景
機能:
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
細胞の位置付け:
Cell membrane>Single-pass type I membrane protein. Cell junction>Desmosome.
組織特異性:
All of the tissues tested and carcinomas.
タンパク質ファミリー:
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
研究領域
· Human Diseases > Cardiovascular diseases > Arrhythmogenic right ventricular cardiomyopathy (ARVC).
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