DHODH Antibody - #DF3991
(1)
(3)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3991, RRID:AB_2836351.
折りたたみ／展開
DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1;
免疫原
- Q02127 PYRD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02127 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T62 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| Y146 | Phosphorylation | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| Y194 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| T217 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| K306 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| Y355 | Phosphorylation | Uniprot | |
| T356 | Phosphorylation | Uniprot | |
| T359 | Phosphorylation | Uniprot | |
| K378 | Ubiquitination | Uniprot |
研究背景
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
The uncleaved transit peptide is required for mitochondrial targeting and proper membrane integration.
Mitochondrion inner membrane>Single-pass membrane protein.
Monomer.
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
研究領域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.