DNAI2 Antibody - #DF4013
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4013, RRID:AB_2836373.
折りたたみ／展開
axonemal; Axonemal dynein intermediate chain 2; CILD9; DNAI 2; Dnai2; DNAI2_HUMAN; Dynein axonemal intermediate chain 2; Dynein axonemal intermediate polypeptide 2; Dynein intermediate chain 2; Dynein intermediate chain 2 axonemal;
免疫原
- Q9GZS0 DNAI2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLEVSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVDLEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEVEEDLA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9GZS0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S298 | Phosphorylation | Uniprot | |
| T301 | Phosphorylation | Uniprot | |
| T331 | Phosphorylation | Uniprot | |
| T337 | Phosphorylation | Uniprot | |
| S344 | Phosphorylation | Uniprot | |
| Y405 | Phosphorylation | Uniprot | |
| Y409 | Phosphorylation | Uniprot | |
| K520 | Acetylation | Uniprot | |
| K522 | Acetylation | Uniprot |
研究背景
Part of the dynein complex of respiratory cilia.
Cytoplasm>Cytoskeleton>Cilium axoneme.
Highly expressed in trachea and testis.
Consists of at least two heavy chains and a number of intermediate and light chains (Probable). Interacts with DNAAF2 (By similarity). Interacts with PIH1D3 (By similarity). Interacts with HEATR2; probably involved in outer arm dynein assembly.
Belongs to the dynein intermediate chain family.
研究領域
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
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