製品: ENDOGL1 Antibody
カタログ: DF4040
タンパク質の説明: Rabbit polyclonal antibody to ENDOGL1
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Sheep, Dog, Chicken
分子量: 41 KD; 41kD(Calculated).
ユニプロット: Q9Y2C4
RRID: AB_2836393

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(80%), Bovine(80%), Sheep(80%), Dog(80%), Chicken(80%)
クローナリティ:
Polyclonal
特異性:
ENDOGL1 Antibody detects endogenous levels of total ENDOGL1.
RRID:
AB_2836393
引用形式: Affinity Biosciences Cat# DF4040, RRID:AB_2836393.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Endo G like 1; Endo G-like 1; Endo/exonuclease (5'-3'), endonuclease G like; ENDOGL 1; ENDOGL1; ENDOGL2; Endonuclease G like 1; Endonuclease G like 2; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; ENGLA; ENGLB; Exog; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9Y2C4 EXOG_HUMAN:

Ubiquitous.

タンパク質配列:
MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
80
Bovine
80
Sheep
80
Dog
80
Chicken
80
Horse
70
Zebrafish
67
Xenopus
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y2C4 基板として

Site PTM Type Enzyme
K4 Ubiquitination
S5 Phosphorylation
K59 Acetylation
K100 Acetylation
K230 Ubiquitination
K327 Ubiquitination
K333 Ubiquitination
K350 Ubiquitination
K355 Ubiquitination

研究背景

機能:

Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.

細胞の位置付け:

Mitochondrion inner membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the DNA/RNA non-specific endonuclease family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.