製品: GNA14 Antibody
カタログ: DF4106
タンパク質の説明: Rabbit polyclonal antibody to GNA14
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
分子量: 42 KD; 42kD(Calculated).
ユニプロット: O95837
RRID: AB_2836397

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(100%), Horse(100%), Rabbit(88%), Dog(100%), Chicken(88%), Xenopus(88%)
クローナリティ:
Polyclonal
特異性:
GNA14 Antibody detects endogenous levels of total GNA14.
RRID:
AB_2836397
引用形式: Affinity Biosciences Cat# DF4106, RRID:AB_2836397.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AU023208; g alpha 14; G alpha-14; G protein alpha subunit 14; G protein subunit alpha 14; G-protein subunit alpha-14; gna14; GNA14_HUMAN; Guanine nucleotide binding protein (G protein) alpha 14; Guanine nucleotide binding protein 14; Guanine nucleotide binding protein alpha 14 subunit; Guanine nucleotide binding protein subunit alpha 14; Guanine nucleotide-binding protein subunit alpha-14; MGC105546; OTTHUMP00000021515; Tieg3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Dog
100
Xenopus
88
Chicken
88
Rabbit
88
Pig
0
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95837 基板として

Site PTM Type Enzyme
S46 Phosphorylation
K48 Ubiquitination
Y147 Phosphorylation
S167 Phosphorylation
T171 Phosphorylation

研究背景

機能:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

サブユニット構造:

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

タンパク質ファミリー:

Belongs to the G-alpha family. G(q) subfamily.

研究領域

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Parasitic > Chagas disease (American trypanosomiasis).

· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.

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