NDUFA9 Antibody - #DF4206
| 製品: | NDUFA9 Antibody |
| カタログ: | DF4206 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFA9 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Rabbit |
| 分子量: | 40 KD; 43kD(Calculated). |
| ユニプロット: | Q16795 |
| RRID: | AB_2836414 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4206, RRID:AB_2836414.
折りたたみ／展開
CI-39kD; Complex I subunit NDUFA9; Complex I-39kD; mitochondrial; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial; NADH Ubiquinone Oxidoreductase 1 alpha subcomplex 9; NADH-ubiquinone oxidoreductase 39 kDa subunit; NDUA9_HUMAN; NDUFA9;
免疫原
- Q16795 NDUA9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAAQSRVVRVLSMSRSAITAIATSVCHGPPCRQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIAQLSKEAGVEKFIHVSHLNANIKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNSFASMHRFGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLFHLVKYIFAVAHRLFLPFPLPLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRWLSAEIEDVKPAKTVNI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16795 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| R75 | Methylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K189 | Acetylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| K234 | Acetylation | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K328 | Acetylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| K348 | Ubiquitination | Uniprot | |
| K373 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Required for proper complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Acetylated on lysine residues. BLOC1S1 is required for acetylation. Acetylated by CLOCK in a circadian manner.
Mitochondrion matrix.
Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction. Interacts with BLOC1S1. Interacts with SLC2A4 (By similarity). Interacts with CLOCK. Interacts with RAB5IF.
Belongs to the complex I NDUFA9 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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