EPN2 Antibody - #DF4045
| 製品: | EPN2 Antibody |
| カタログ: | DF4045 |
| タンパク質の説明: | Rabbit polyclonal antibody to EPN2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Rabbit |
| 分子量: | 68 KD; 68kD(Calculated). |
| ユニプロット: | O95208 |
| RRID: | AB_2836419 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4045, RRID:AB_2836419.
折りたたみ／展開
EHB21; EPN 2; Epn2; EPN2_HUMAN; EPS 15 interacting protein 2; EPS-15-interacting protein 2; Eps15 binding protein; Epsin 2; Epsin-2; Epsin2; KIAA1065; OTTHUMP00000065808; OTTHUMP00000065809; OTTHUMP00000065810; OTTHUMP00000065811; OTTHUMP00000065889;
免疫原
- O95208 EPN2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPNGDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPSASTNQTNPWGGPAAPASTSDPWPSFGTKPAASIDPWGVPTGATVQSVPKNSDPWAASQQPASSAGKRASDAWGAVSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSLPSQNNGTTSPDPFESQPLTVASSKPSSARKTPESFLGPNAALVNLDSLVTRPAPPAQSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLRGSPVLGTSTSFGPGPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVGIPPSAAQATGTTNPFLL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95208 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T2 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| K11 | Ubiquitination | Uniprot | |
| K69 | Ubiquitination | Uniprot | |
| Y83 | Phosphorylation | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| T150 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| R170 | Methylation | Uniprot | |
| S172 | Phosphorylation | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| S182 | Phosphorylation | Uniprot | |
| Y186 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| T249 | Phosphorylation | Uniprot | |
| T272 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S287 | Phosphorylation | Uniprot | |
| T316 | Phosphorylation | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| S327 | Phosphorylation | Uniprot | |
| S408 | Phosphorylation | Uniprot | |
| S420 | Phosphorylation | Uniprot | |
| K423 | Acetylation | Uniprot | |
| K423 | Methylation | Uniprot | |
| K423 | Ubiquitination | Uniprot | |
| S426 | Phosphorylation | Uniprot | |
| S486 | Phosphorylation | Uniprot | |
| S492 | Phosphorylation | Uniprot | |
| S504 | Phosphorylation | Uniprot | |
| T508 | Phosphorylation | Uniprot | |
| S570 | Phosphorylation | Uniprot | |
| S622 | Phosphorylation | Uniprot | |
| S628 | Phosphorylation | Uniprot |
研究背景
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Ubiquitinated.
Cytoplasm. Cytoplasmic vesicle>Clathrin-coated vesicle.
Note: In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
Highest expression is found in brain. Detected at lower levels in lung and liver.
Binds EPS15 (By similarity). Interacts with ITSN1 (By similarity). Binds AP-2 and clathrin. Interacts with UBQLN2.
The NPF repeat domain is involved in EPS15 binding.
The DPW repeat domain is involved in AP-2 and clathrin binding.
Belongs to the epsin family.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.