EPN3 Antibody - #DF4046
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4046, RRID:AB_2836420.
折りたたみ／展開
EPN 3; EPS 15 interacting protein 3; Epsin 3; Epsin3; FLJ20778; MGC129899;
免疫原
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
- Q9H201 EPN3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H201 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T2 | Phosphorylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| Y17 | Phosphorylation | Uniprot | |
| S18 | Phosphorylation | Uniprot | |
| K23 | Ubiquitination | Uniprot | |
| Y83 | Phosphorylation | Uniprot | |
| Y101 | Phosphorylation | Uniprot | |
| T102 | Phosphorylation | Uniprot | |
| Y111 | Phosphorylation | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| Y172 | Phosphorylation | Uniprot | |
| Y176 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S182 | Phosphorylation | Uniprot | |
| Y186 | Phosphorylation | Uniprot | |
| Y195 | Phosphorylation | Uniprot | |
| T206 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S258 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot | |
| S368 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| S460 | Phosphorylation | Uniprot | |
| T495 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| S534 | Phosphorylation | Uniprot |
研究背景
Cytoplasm. Cytoplasm>Perinuclear region. Cytoplasmic vesicle>Clathrin-coated vesicle. Nucleus.
Note: Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.
Detected in migrating keratinocytes from wounded skin, but not in differentiating keratinocytes or in normal skin. Detected in chronic wounds, basal cell carcinoma and ulcerative colitis.
Belongs to the epsin family.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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