TUBGCP6 Antibody - #DF4077
(2)
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Rat
クローナリティ:
Polyclonal
特異性:
TUBGCP6 Antibody detects endogenous levels of total TUBGCP6.
RRID:
AB_2836451
引用形式: Affinity Biosciences Cat# DF4077, RRID:AB_2836451.
引用形式: Affinity Biosciences Cat# DF4077, RRID:AB_2836451.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
Gamma tubulin complex component 6; GCP 6; MCCRP; MCPHCR; TUBGCP6; tubulin, gamma complex associated protein 6;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- Q96RT7 GCP6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPDMSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGSGPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQVMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNADLSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERVGCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVLIGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLDSLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVGAVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWVYSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGKTINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEEKELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERRQAARQEELDDDFSYARELRDRERRLKSLEEELERKARQALVDHYSKLSAEAARREQKALWRIQRHRLESARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSAEQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEPSVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPGPLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQVSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTHGHVSNASISLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPTRPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNTHVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSTVLDCGPRLPVEVGPSLSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDLSPNWPLNSQEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLRPVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFFVELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQCSLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCVSKYSGVFSFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVTWCEFRARLATVGDLEEIQRAHAEYLHKAVFRGLLTEKAAPVMNVIHSIFSLVLKFRSQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQPHLEDFLLRINFNNYYQDA
PTMs - Q96RT7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K137 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| T178 | Phosphorylation | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| T210 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| K322 | Ubiquitination | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| S392 | Phosphorylation | O00444 (PLK4) | Uniprot |
| Y439 | Phosphorylation | Uniprot | |
| Y443 | Phosphorylation | Uniprot | |
| S629 | Phosphorylation | Uniprot | |
| K638 | Ubiquitination | Uniprot | |
| S654 | Phosphorylation | Uniprot | |
| S657 | Phosphorylation | Uniprot | |
| K669 | Ubiquitination | Uniprot | |
| S693 | Phosphorylation | Uniprot | |
| K710 | Ubiquitination | Uniprot | |
| K746 | Ubiquitination | Uniprot | |
| K766 | Ubiquitination | Uniprot | |
| S831 | Phosphorylation | Uniprot | |
| S852 | Phosphorylation | Uniprot | |
| T865 | Phosphorylation | Uniprot | |
| T963 | Phosphorylation | Uniprot | |
| S964 | Phosphorylation | Uniprot | |
| Y1039 | Phosphorylation | Uniprot | |
| S1041 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1057 | Phosphorylation | Uniprot | |
| S1060 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1068 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1087 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1095 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1111 | Phosphorylation | Uniprot | |
| S1114 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1122 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1141 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1149 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1168 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1176 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1195 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1203 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1222 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1230 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1237 | Phosphorylation | Uniprot | |
| S1249 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1257 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1283 | Phosphorylation | Uniprot | |
| S1296 | Phosphorylation | Uniprot | |
| S1397 | Phosphorylation | Uniprot | |
| S1437 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1465 | Phosphorylation | O00444 (PLK4) | Uniprot |
| S1655 | Phosphorylation | Uniprot | |
| T1727 | Phosphorylation | Uniprot | |
| S1742 | Phosphorylation | Uniprot |
研究背景
機能:
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
細胞の位置付け:
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
サブユニット構造:
Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.
タンパク質ファミリー:
Belongs to the TUBGCP family.
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