GAS1 Antibody - #DF4098
(3)
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
GAS1 Antibody detects endogenous levels of total GAS1.
RRID:
AB_2836472
引用形式: Affinity Biosciences Cat# DF4098, RRID:AB_2836472.
引用形式: Affinity Biosciences Cat# DF4098, RRID:AB_2836472.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
GAS-1; Gas1; GAS1_HUMAN; Growth arrest-specific protein 1; Growth-arrest-specific protein 1 precursor;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- P54826 GAS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVAALLGGGGEARGGTVPGAWLCLMALLQLLGSAPRGSGLAHGRRLICWQALLQCQGEPECSYAYNQYAEACAPVLAQHGGGDAPGAAAAAFPASAASFSSRWRCPSHCISALIQLNHTRRGPALEDCDCAQDENCKSTKRAIEPCLPRTSGGGAGGPGAGGVMGCTEARRRCDRDSRCNLALSRYLTYCGKVFNGLRCTDECRTVIEDMLAMPKAALLNDCVCDGLERPICESVKENMARLCFGAELGNGPGSSGSDGGLDDYYDEDYDDEQRTGGAGGEQPLDDDDGVPHPPRPGSGAAASGGRGDLPYGPGRRSSGGGGRLAPRGAWTPLASILLLLLGPLF
PTMs - P54826 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S184 | Phosphorylation | Uniprot | |
| K192 | Ubiquitination | Uniprot |
研究背景
機能:
Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
細胞の位置付け:
Cell membrane>Lipid-anchor.
研究領域
· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway. (View pathway)
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