HLA-H Antibody - #DF4117
(2)
製品説明
ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Polyclonal
特異性:
HLA-H Antibody detects endogenous levels of total HLA-H.
RRID:
AB_2836482
引用形式: Affinity Biosciences Cat# DF4117, RRID:AB_2836482.
引用形式: Affinity Biosciences Cat# DF4117, RRID:AB_2836482.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
HLA-12.4; HLA-AR; HLA-H; HLAH; HLAHP; Major histocompatibility complex, class I, H (pseudogene); MHC class I antigen H; Putative HLA class I histocompatibility antigen, alpha chain H;
免疫原
免疫原:
Uniprot:
タンパク質配列:
- P01893 HLAH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVLMAPRTLLLLLSGALALTQTWARSHSMRYFYTTMSRPGAGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPKYWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGPDGPFLRGYEQHAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAARRAEQRRVYLEGEFVEWLRRYLENGKETLQRADPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTVPIVGIVAGLVLLVAVVTGAVVAAVMWRKKSSDRKGGSYSQAASSNSAQGSDVSLTA
PTMs - P01893 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K168 | Ubiquitination | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K200 | Ubiquitination | Uniprot | |
| K267 | Ubiquitination | Uniprot | |
| S350 | Phosphorylation | Uniprot |
研究背景
機能:
Involved in the presentation of foreign antigens to the immune system.
細胞の位置付け:
Cell membrane>Single-pass membrane protein.
サブユニット構造:
Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).
タンパク質ファミリー:
Belongs to the MHC class I family.
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