ICAM2 Antibody - #DF4131
| 製品: | ICAM2 Antibody |
| カタログ: | DF4131 |
| タンパク質の説明: | Rabbit polyclonal antibody to ICAM2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 分子量: | 30 KD; 31kD(Calculated). |
| ユニプロット: | P13598 |
| RRID: | AB_2836496 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4131, RRID:AB_2836496.
折りたたみ／展開
CD102; CD102 antigen; ICAM 2; Intercellular adhesion molecule 2; Ly60;
免疫原
- P13598 ICAM2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
PTMs - P13598 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N47 | N-Glycosylation | Uniprot | |
| N82 | N-Glycosylation | Uniprot | |
| N105 | N-Glycosylation | Uniprot | |
| N153 | N-Glycosylation | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| N176 | N-Glycosylation | Uniprot | |
| N187 | N-Glycosylation | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| T259 | Phosphorylation | Uniprot | |
| Y260 | Phosphorylation | Uniprot |
研究背景
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Membrane>Single-pass type I membrane protein. Cell projection>Microvillus.
Note: Co-localizes with RDX, EZR and MSN in microvilli.
Interacts with RDX, EZR and MSN.
Belongs to the immunoglobulin superfamily. ICAM family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
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