LFA3 Antibody - #DF4147
| 製品: | LFA3 Antibody |
| カタログ: | DF4147 |
| タンパク質の説明: | Rabbit polyclonal antibody to LFA3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 分子量: | 28 KD; 28kD(Calculated). |
| ユニプロット: | P19256 |
| RRID: | AB_2836512 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4147, RRID:AB_2836512.
折りたたみ／展開
AG3; CD58; CD58 antigen (lymphocyte function associated antigen 3)1; CD58 antigen; CD58 antigen, (lymphocyte function associated antigen 3); CD58 molecule; FLJ23181; FLJ43722; LFA 3; LFA-3; LFA3; LFA3_HUMAN; Lymphocyte Function Associated Antigen Type 3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA 3; Surface glycoprotein LFA-3;
免疫原
- P19256 LFA3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVAGSDAGRALGVLSVVCLLHCFGFISCFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDEDEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSIILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTNSN
PTMs - P19256 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K62 | Ubiquitination | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| S209 | Phosphorylation | Uniprot |
研究背景
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Cell membrane>Single-pass type I membrane protein.
Interacts with CD2. Interacts with CMTM6.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
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