MAD2L1BP Antibody - #DF4150
| 製品: | MAD2L1BP Antibody |
| カタログ: | DF4150 |
| タンパク質の説明: | Rabbit polyclonal antibody to MAD2L1BP |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 31 KD; 31kD(Calculated). |
| ユニプロット: | Q15013 |
| RRID: | AB_2836515 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4150, RRID:AB_2836515.
折りたたみ／展開
Caught by MAD2 protein; CMT2; dJ261G23.1; KIAA0110; MAD2L1 binding protein; MAD2L1 binding protein isoform 2; MAD2L1-binding protein; Mad2l1bp; MD2BP_HUMAN; MGC11282; OTTHUMP00000016496; RP1 261G23.6;
免疫原
- Q15013 MD2BP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15013 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S23 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| K78 | Ubiquitination | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y98 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| Y232 | Phosphorylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| S251 | Phosphorylation | Uniprot |
研究背景
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Nucleus. Cytoplasm>Cytoskeleton>Spindle.
Note: During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
Interacts with MAD2L1.
Belongs to the MAD2L1BP family.
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