製品: MRPL49 Antibody
カタログ: DF4177
タンパク質の説明: Rabbit polyclonal antibody to MRPL49
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 20 KD; 19kD(Calculated).
ユニプロット: Q13405
RRID: AB_2836542

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(89%), Bovine(82%), Horse(89%), Sheep(82%), Rabbit(88%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
MRPL49 Antibody detects endogenous levels of total MRPL49.
RRID:
AB_2836542
引用形式: Affinity Biosciences Cat# DF4177, RRID:AB_2836542.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

39S ribosomal protein L49 mitochondrial; C11orf4; Chromosome 11 open reading frame 4; L49mt; MGC10656; Mitochondrial ribosomal protein L49; MRP L49; Neighbor of FAU; Next to FAU; NOF; NOF1; Protein NOF1; RM49;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q13405 RM49_HUMAN:

Ubiquitous.

タンパク質配列:
MAATMFRATLRGWRTGVQRGCGLRLLSQTQGPPDYPRFVESVDEYQFVERLLPATRIPDPPKHEHYPTPSGWQPPRDPPPNLPYFVRRSRMHNIPVYKDITHGNRQMTVIRKVEGDIWALQKDVEDFLSPLLGKTPVTQVNEVTGTLRIKGYFDQELKAWLLEKGF

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
89
Horse
89
Rabbit
88
Bovine
82
Sheep
82
Dog
82
Zebrafish
70
Xenopus
60
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q13405 基板として

Site PTM Type Enzyme
Y45 Phosphorylation
S129 Phosphorylation
T135 Phosphorylation
T138 Phosphorylation
Y152 Phosphorylation

研究背景

細胞の位置付け:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins. Interacts with OXA1L (By similarity).

タンパク質ファミリー:

Belongs to the mitochondrion-specific ribosomal protein mL49 family.

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