製品: MYOM2 Antibody
カタログ: DF4195
タンパク質の説明: Rabbit polyclonal antibody to MYOM2
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Sheep, Rabbit, Chicken
分子量: 165 KD; 165kD(Calculated).
ユニプロット: P54296
RRID: AB_2836560

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(82%), Bovine(100%), Sheep(100%), Rabbit(100%), Chicken(80%)
クローナリティ:
Polyclonal
特異性:
MYOM2 Antibody detects endogenous levels of total MYOM2.
RRID:
AB_2836560
引用形式: Affinity Biosciences Cat# DF4195, RRID:AB_2836560.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

165 kDa connectin associated protein; 165 kDa connectin-associated protein; 165 kDa titin associated protein; 165 kDa titin-associated protein; M band protein; M protein; M-protein; MYOM 2; MYOM2; MYOM2_HUMAN; Myomesin (M protein) 2 (165kD); Myomesin (M protein) 2 165kDa; Myomesin (M protein) 2; Myomesin 2; Myomesin family member 2; Myomesin-2; Titin associated protein 165 kD; Titin associated protein; TTNAP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASASAAGQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
82
Chicken
80
Horse
55
Xenopus
55
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P54296 基板として

Site PTM Type Enzyme
S2 Phosphorylation
S19 Phosphorylation
Y20 Phosphorylation
Y32 Phosphorylation
S34 Phosphorylation
S49 Phosphorylation
S58 Phosphorylation
S59 Phosphorylation
T61 Phosphorylation
T66 Phosphorylation
S76 Phosphorylation P17612 (PRKACA)
T77 Phosphorylation
S91 Phosphorylation
Y96 Phosphorylation
K100 Acetylation
S106 Phosphorylation
S162 Phosphorylation
S192 Phosphorylation
T296 Phosphorylation
Y317 Phosphorylation
Y442 Phosphorylation
S462 Phosphorylation
Y500 Phosphorylation
S530 Phosphorylation
S555 Phosphorylation
S567 Phosphorylation
S594 Phosphorylation
S597 Phosphorylation
T600 Phosphorylation
S601 Phosphorylation
S613 Phosphorylation
T676 Phosphorylation
S737 Phosphorylation
K749 Acetylation
S828 Phosphorylation
Y838 Phosphorylation
Y847 Phosphorylation
Y871 Phosphorylation
S875 Phosphorylation
S946 Phosphorylation
Y947 Phosphorylation
S951 Phosphorylation
Y968 Phosphorylation
Y1024 Phosphorylation
Y1047 Phosphorylation
S1057 Phosphorylation
T1070 Phosphorylation
S1081 Phosphorylation
T1089 Phosphorylation
S1099 Phosphorylation
S1102 Phosphorylation
T1112 Phosphorylation
Y1135 Phosphorylation
S1272 Phosphorylation
S1273 Phosphorylation
S1274 Phosphorylation
Y1400 Phosphorylation
Y1424 Phosphorylation
Y1436 Phosphorylation
S1461 Phosphorylation

研究背景

機能:

Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

細胞の位置付け:

Cytoplasm>Myofibril>Sarcomere>M line.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with TTN/titin.

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