CYB5R3 Antibody - #DF4212
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4212, RRID:AB_2836563.
折りたたみ／展開
B5R; Cyb5r3; Cytochrome b5 reductase 3; Cytochrome b5 reductase; DIA1; Diaphorase 1; Diaphorase-1; NADH cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form; NB5R3_HUMAN; OTTHUMP00000028761; OTTHUMP00000198435; OTTHUMP00000198574; OTTHUMP00000198662; OTTHUMP00000198665;
免疫原
A synthesized peptide derived from human CYB5R3, corresponding to a region within C-terminal amino acids.
- P00387 NB5R3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFVF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00387 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| G2 | Myristoylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| T31 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| K42 | Acetylation | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| Y43 | Phosphorylation | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| S146 | Phosphorylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| T171 | Phosphorylation | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| T185 | Phosphorylation | Uniprot | |
| K196 | Acetylation | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| Y248 | Phosphorylation | Uniprot |
研究背景
Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
Endoplasmic reticulum membrane>Lipid-anchor>Cytoplasmic side. Mitochondrion outer membrane>Lipid-anchor>Cytoplasmic side.
Cytoplasm.
Note: Produces the soluble form found in erythrocytes.
Isoform 2 is expressed at late stages of erythroid maturation.
Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MTARC2.
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
研究領域
· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.