NUP107 Antibody - #DF4250
製品: | NUP107 Antibody |
カタログ: | DF4250 |
タンパク質の説明: | Rabbit polyclonal antibody to NUP107 |
アプリケーション: | WB IHC |
反応性: | Human, Mouse, Rat |
予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 106 KD; 106kD(Calculated). |
ユニプロット: | P57740 |
RRID: | AB_2836601 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4250, RRID:AB_2836601.
折りたたみ/展開
107 kDa nucleoporin; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP107; NUP84; NUP84, yeast, homolog of; OTTHUMP00000240604; OTTHUMP00000240606;
免疫原
- P57740 NU107_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P57740 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
M1 | Acetylation | Uniprot | |
S4 | Phosphorylation | Uniprot | |
S10 | Phosphorylation | P24941 (CDK2) | Uniprot |
S11 | Phosphorylation | P24941 (CDK2) | Uniprot |
T22 | Phosphorylation | Uniprot | |
K25 | Methylation | Uniprot | |
S37 | Phosphorylation | Uniprot | |
T45 | Phosphorylation | Uniprot | |
T46 | Phosphorylation | Uniprot | |
T55 | Phosphorylation | Uniprot | |
S57 | Phosphorylation | Uniprot | |
S58 | Phosphorylation | Uniprot | |
R60 | Methylation | Uniprot | |
T64 | Phosphorylation | Uniprot | |
T66 | Phosphorylation | Uniprot | |
S67 | Phosphorylation | Uniprot | |
R68 | Methylation | Uniprot | |
S69 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
C78 | S-Nitrosylation | Uniprot | |
T82 | Phosphorylation | Uniprot | |
K85 | Ubiquitination | Uniprot | |
S86 | Phosphorylation | Uniprot | |
S119 | Phosphorylation | Uniprot | |
S129 | Phosphorylation | Uniprot | |
S153 | Phosphorylation | Uniprot | |
S156 | Phosphorylation | Uniprot | |
T196 | Phosphorylation | Uniprot | |
K201 | Ubiquitination | Uniprot | |
S232 | Phosphorylation | Uniprot | |
T251 | Phosphorylation | Uniprot | |
Y296 | Phosphorylation | Uniprot | |
K305 | Methylation | Uniprot | |
K305 | Ubiquitination | Uniprot | |
S315 | Phosphorylation | Uniprot | |
T321 | Phosphorylation | Uniprot | |
K332 | Ubiquitination | Uniprot | |
K348 | Ubiquitination | Uniprot | |
K382 | Ubiquitination | Uniprot | |
K408 | Ubiquitination | Uniprot | |
K491 | Ubiquitination | Uniprot | |
K501 | Ubiquitination | Uniprot | |
K502 | Ubiquitination | Uniprot | |
Y512 | Phosphorylation | Uniprot | |
S569 | Phosphorylation | Uniprot | |
K626 | Ubiquitination | Uniprot | |
K637 | Ubiquitination | Uniprot | |
K646 | Ubiquitination | Uniprot | |
K690 | Ubiquitination | Uniprot | |
S702 | Phosphorylation | Uniprot | |
K709 | Acetylation | Uniprot | |
K709 | Ubiquitination | Uniprot | |
K714 | Acetylation | Uniprot | |
K773 | Ubiquitination | Uniprot | |
K785 | Ubiquitination | Uniprot | |
K803 | Ubiquitination | Uniprot | |
K814 | Ubiquitination | Uniprot | |
K816 | Ubiquitination | Uniprot | |
K837 | Ubiquitination | Uniprot |
研究背景
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis.
Nucleus membrane. Nucleus>Nuclear pore complex. Chromosome>Centromere>Kinetochore.
Note: Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755).
Ubiquitously expressed in fetal and adult tissues.
Part of the nuclear pore complex (NPC). Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96; this complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus. Does not interact with TPR. Interacts with ZNF106 (By similarity).
Belongs to the nucleoporin Nup84/Nup107 family.
研究領域
· Genetic Information Processing > Translation > RNA transport.
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