製品: NUP160 Antibody
カタログ: DF4251
タンパク質の説明: Rabbit polyclonal antibody to NUP160
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 140 KD; 162kD(Calculated).
ユニプロット: Q12769
RRID: AB_2836602

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(91%), Bovine(100%), Horse(91%), Sheep(100%), Rabbit(82%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
NUP160 Antibody detects endogenous levels of total NUP160.
RRID:
AB_2836602
引用形式: Affinity Biosciences Cat# DF4251, RRID:AB_2836602.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

160 kDa nucleoporin; DKFZp686M14102; FLJ22583; KIAA0197; MGC150678; MGC150679; NU160_HUMAN; Nuclear pore complex protein Nup160; Nucleoporin 160kD; Nucleoporin 160kDa; Nucleoporin Nup160; NUP 160; NUP120; Nup160;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERNLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Pig
91
Horse
91
Dog
82
Rabbit
82
Zebrafish
70
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q12769 基板として

Site PTM Type Enzyme
S44 Phosphorylation
S49 Phosphorylation
K93 Ubiquitination
K106 Acetylation
K131 Ubiquitination
Y246 Phosphorylation
K258 Ubiquitination
K314 Acetylation
K343 Ubiquitination
Y457 Phosphorylation
S460 Phosphorylation
T463 Phosphorylation
T468 Phosphorylation
R481 Methylation
S490 Phosphorylation
K495 Ubiquitination
K608 Ubiquitination
T683 Phosphorylation
K689 Ubiquitination
K722 Ubiquitination
Y773 Phosphorylation
Y774 Phosphorylation
K833 Ubiquitination
K925 Ubiquitination
S935 Phosphorylation
K939 Ubiquitination
S949 Phosphorylation
T957 Phosphorylation
K965 Ubiquitination
K995 Ubiquitination
K1006 Methylation
K1006 Ubiquitination
K1096 Ubiquitination
K1120 Ubiquitination
Y1139 Phosphorylation
S1147 Phosphorylation
Y1151 Phosphorylation
S1157 Phosphorylation
K1159 Ubiquitination
C1166 S-Nitrosylation
K1185 Ubiquitination
T1240 Phosphorylation
K1249 Ubiquitination
K1252 Ubiquitination
K1300 Ubiquitination
K1415 Ubiquitination
K1422 Ubiquitination

研究背景

機能:

Functions as a component of the nuclear pore complex (NPC). Involved in poly(A)+ RNA transport.

細胞の位置付け:

Nucleus>Nuclear pore complex.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Part of the nuclear pore complex (NPC). Forms part of the NUP160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and NUP96. This complex plays a role in RNA export and in tethering NUP98 and NUP153 to the nucleus.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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