NUP93 Antibody - #DF4252
| 製品: | NUP93 Antibody |
| カタログ: | DF4252 |
| タンパク質の説明: | Rabbit polyclonal antibody to NUP93 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Dog |
| 分子量: | 93 KD; 93kD(Calculated). |
| ユニプロット: | Q8N1F7 |
| RRID: | AB_2836603 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4252, RRID:AB_2836603.
折りたたみ／展開
2410008G02Rik; 93 kDa nucleoporin; CBP-interacting protein 4; Dead eye protein; Dye; KIAA0095; MGC21106; NIC96; NIC96, S. cerevisiae, homolog of; Nuclear pore complex protein Nup93; Nucleoporin 93; Nucleoporin 93kDa; Nucleoporin Nup93;
免疫原
- Q8N1F7 NUP93_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYISDVGPPGRSSLDNIEMAYARQIYIYNEKIVNGHLQPNLVDLCASVAELDDKSISDMWTMVKQMTDVLLTPATDALKNRSSVEVRMEFVRQALAYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPLPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVNRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDVTDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAVAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCLRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIERLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSSSRPQRVIEDRDSQLRSQARTLITFAGMIPYRTSGDTNARLVQMEVLMN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8N1F7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T3 | Phosphorylation | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| T47 | Phosphorylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| T51 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| T55 | Phosphorylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| R67 | Methylation | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K103 | Acetylation | Uniprot | |
| K103 | Sumoylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| R120 | Methylation | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| T159 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S165 | Phosphorylation | Uniprot | |
| Y166 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| Y185 | Phosphorylation | Uniprot | |
| Y190 | Phosphorylation | Uniprot | |
| T231 | Phosphorylation | Uniprot | |
| T236 | Phosphorylation | Uniprot | |
| K243 | Ubiquitination | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| T350 | Phosphorylation | Uniprot | |
| K359 | Ubiquitination | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| T367 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| K387 | Ubiquitination | Uniprot | |
| Y391 | Phosphorylation | Uniprot | |
| K409 | Ubiquitination | Uniprot | |
| Y413 | Phosphorylation | Uniprot | |
| K417 | Ubiquitination | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| R434 | Methylation | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| T536 | Phosphorylation | Uniprot | |
| Y550 | Phosphorylation | Uniprot | |
| K558 | Ubiquitination | Uniprot | |
| S560 | Phosphorylation | Uniprot | |
| S571 | Phosphorylation | Uniprot | |
| K586 | Ubiquitination | Uniprot | |
| K594 | Ubiquitination | Uniprot | |
| K600 | Ubiquitination | Uniprot | |
| S603 | Phosphorylation | Uniprot | |
| K606 | Sumoylation | Uniprot | |
| K606 | Ubiquitination | Uniprot | |
| K611 | Ubiquitination | Uniprot | |
| S614 | Phosphorylation | Uniprot | |
| K619 | Acetylation | Uniprot | |
| K619 | Ubiquitination | Uniprot | |
| K627 | Ubiquitination | Uniprot | |
| K633 | Ubiquitination | Uniprot | |
| K637 | Acetylation | Uniprot | |
| K637 | Ubiquitination | Uniprot | |
| K644 | Ubiquitination | Uniprot | |
| S647 | Phosphorylation | Uniprot | |
| S654 | Phosphorylation | Uniprot | |
| S658 | Phosphorylation | Uniprot | |
| K660 | Ubiquitination | Uniprot | |
| K664 | Ubiquitination | Uniprot | |
| K718 | Ubiquitination | Uniprot | |
| S726 | Phosphorylation | Uniprot | |
| T758 | Phosphorylation | Uniprot | |
| K764 | Ubiquitination | Uniprot | |
| T766 | Phosphorylation | Uniprot | |
| S767 | Phosphorylation | Uniprot | |
| S770 | Phosphorylation | Uniprot | |
| S771 | Phosphorylation | Uniprot | |
| S772 | Phosphorylation | Uniprot |
研究背景
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
Nucleus membrane>Peripheral membrane protein. Nucleus>Nuclear pore complex. Nucleus envelope.
Note: Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.
Part of the nuclear pore complex (NPC). Component of the p62 complex, a complex composed of NUP62 and NUP54. Forms a complex with NUP35, NUP155, NUP205 and lamin B; the interaction with NUP35 is direct. Does not interact with TPR. Interacts with SMAD4 and IPO7; translocates SMAD4 to the nucleus through the NPC upon BMP7 stimulation resulting in activation of SMAD4 signaling.
Belongs to the nucleoporin interacting component (NIC) family.
研究領域
· Genetic Information Processing > Translation > RNA transport.
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