SLC22A3 Antibody - #DF4268
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| 製品: | SLC22A3 Antibody |
| カタログ: | DF4268 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC22A3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 61 KD; 61kD(Calculated). |
| ユニプロット: | O75751 |
| RRID: | AB_2836619 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4268, RRID:AB_2836619.
折りたたみ／展開
EMT; EMT organic cation transporter 3; EMTH; Extraneuronal monoamine transporter; OCT 3; OCT3; Orct 3; Orct3; Organic cation transporter 3; S22A3_HUMAN; SLC22 A3; SLC22A 3; Slc22a3; Solute carrier family 22 (extraneuronal monoamine transporter) member 3; Solute carrier family 22 (organic cation transporter) member 3; Solute carrier family 22 member 3;
免疫原
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.
- O75751 S22A3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHSCKCGRNKKTPVSRSHL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75751 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S508 | Phosphorylation | Uniprot | |
| T520 | Phosphorylation | Uniprot |
研究背景
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Membrane>Multi-pass membrane protein.
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
研究領域
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
参考文献
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