製品: PEX14 Antibody
カタログ: DF4284
タンパク質の説明: Rabbit polyclonal antibody to PEX14
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Xenopus
分子量: 38 KD; 41kD(Calculated).
ユニプロット: O75381
RRID: AB_2836635

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(85%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Xenopus(92%)
クローナリティ:
Polyclonal
特異性:
PEX14 Antibody detects endogenous levels of total PEX14.
RRID:
AB_2836635
引用形式: Affinity Biosciences Cat# DF4284, RRID:AB_2836635.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

dJ734G22.2; NAPP2; NF E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal biogenesis factor 14; Peroxisomal membrane anchor protein PEX14; Peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; pex14; PEX14_HUMAN; Pex14p; PTS1 receptor docking protein; PTS1 receptor-docking protein;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MASSEQAEQPSQPSSTPGSENVLPREPLIATAVKFLQNSRVRQSPLATRRAFLKKKGLTDEEIDMAFQQSGTAADEPSSLGPATQVVPVQPPHLISQPYSPAGSRWRDYGALAIIMAGIAFGFHQLYKKYLLPLILGGREDRKQLERMEAGLSELSGSVAQTVTQLQTTLASVQELLIQQQQKIQELAHELAAAKATTSTNWILESQNINELKSEINSLKGLLLNRRQFPPSPSAPKIPSWQIPVKSPSPSSPAAVNHHSSSDISPVSNESTSSSPGKEGHSPEGSTVTYHLLGPQEEGEGVVDVKGQVRMEVQGEEEKREDKEDEEDEEDDDVSHVDEEDCLGVQREDRRGGDGQINEQVEKLRRPEGASNESERD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Rabbit
100
Xenopus
92
Zebrafish
85
Dog
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75381 基板として

Site PTM Type Enzyme
A2 Acetylation
T16 Phosphorylation
K34 Acetylation
K34 Ubiquitination
S44 Phosphorylation
K195 Ubiquitination
K213 Ubiquitination
K220 Ubiquitination
S232 Phosphorylation
S234 Phosphorylation
K246 Ubiquitination
S249 Phosphorylation
S252 Phosphorylation
S260 Phosphorylation
S261 Phosphorylation
S262 Phosphorylation
S265 Phosphorylation
S275 Phosphorylation
S282 Phosphorylation
S286 Phosphorylation
T289 Phosphorylation
Y290 Phosphorylation
S335 Phosphorylation
R351 Methylation
K363 Ubiquitination
S374 Phosphorylation

研究背景

機能:

Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.

細胞の位置付け:

Peroxisome membrane>Peripheral membrane protein>Cytoplasmic side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with PEX5, PEX13 and PEX19. Interacts with tubulin.

タンパク質ファミリー:

Belongs to the peroxin-14 family.

研究領域

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

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