PIGX Antibody - #DF4293
| 製品: | PIGX Antibody |
| カタログ: | DF4293 |
| タンパク質の説明: | Rabbit polyclonal antibody to PIGX |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Dog |
| 分子量: | 26 KD; 29kD(Calculated). |
| ユニプロット: | Q8TBF5 |
| RRID: | AB_2836644 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4293, RRID:AB_2836644.
折りたたみ／展開
GPI mannosyltransferase subunit; Phosphatidylinositol glycan class X; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X; Pigx; PIGX_HUMAN;
免疫原
- Q8TBF5 PIGX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARVAAVRAAAWLLLGAATGLTRGPAAAFTAARSDAGIRAMCSEIILRQEVLKDGFHRDLLIKVKFGESIEDLHTCRLLIKQDIPAGLYVDPYELASLRERNITEAVMVSENFDIEAPNYLSKESEVLIYARRDSQCIDCFQAFLPVHCRYHRPHSEDGEASIVVNNPDLLMFCDQEFPILKCWAHSEVAAPCALENEDICQWNKMKYKSVYKNVILQVPVGLTVHTSLVCSVTLLITILCSTLILVAVFKYGHFSL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8TBF5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T31 | O-Glycosylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K82 | Ubiquitination | Uniprot |
研究背景
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
N-glycosylated.
Endoplasmic reticulum membrane>Single-pass type I membrane protein.
Interacts with PIGM.
Belongs to the PIGX family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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