製品: CDC40 Antibody
カタログ: DF4326
タンパク質の説明: Rabbit polyclonal antibody to CDC40
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat, Monkey
予測: Pig, Bovine, Sheep, Rabbit, Dog
分子量: 66 KD; 66kD(Calculated).
ユニプロット: O60508
RRID: AB_2836694

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat,Monkey
予測:
Pig(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
CDC40 Antibody detects endogenous levels of total CDC40.
RRID:
AB_2836694
引用形式: Affinity Biosciences Cat# DF4326, RRID:AB_2836694.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cdc40; Cell division cycle 40; Cell division cycle 40 homolog; EH binding protein 3; EH-binding protein 3; Ehb3; hPRP17; Pre mRNA processing factor 17; Pre mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRP17_HUMAN; PRPF17;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
71
Zebrafish
71
Chicken
71
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O60508 基板として

Site PTM Type Enzyme
S2 Phosphorylation
Y12 Phosphorylation
S14 Phosphorylation
S16 Phosphorylation
S18 Phosphorylation
S20 Phosphorylation
S22 Phosphorylation
S24 Phosphorylation
S27 Phosphorylation
S43 Phosphorylation
S45 Phosphorylation
S46 Phosphorylation
S49 Phosphorylation
S56 Phosphorylation
Y81 Phosphorylation
T84 Phosphorylation
Y85 Phosphorylation
Y114 Phosphorylation
Y135 Phosphorylation
Y137 Phosphorylation
K198 Ubiquitination
K226 Acetylation
K228 Acetylation
K380 Ubiquitination
K387 Ubiquitination
K399 Acetylation
S435 Phosphorylation

研究背景

機能:

Required for pre-mRNA splicing as component of the activated spliceosome.

細胞の位置付け:

Nucleus. Nucleus speckle.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Component of the pre-catalytic and catalytic spliceosome complexes. Component of the postcatalytic spliceosome P complex.

研究領域

· Genetic Information Processing > Transcription > Spliceosome.

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