製品: PRPF38A Antibody
カタログ: DF4329
タンパク質の説明: Rabbit polyclonal antibody to PRPF38A
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 40 KD; 37kD(Calculated).
ユニプロット: Q8NAV1
RRID: AB_2836697

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(80%)
クローナリティ:
Polyclonal
特異性:
PRPF38A Antibody detects endogenous levels of total PRPF38A.
RRID:
AB_2836697
引用形式: Affinity Biosciences Cat# DF4329, RRID:AB_2836697.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38 (yeast) domain containing A; PRP38 pre mRNA processing factor 38 domain containing A; prpf38a; RGD1311129; RP23-406B13.4; RP5 965L7.1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGVYGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
80
Zebrafish
60
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NAV1 基板として

Site PTM Type Enzyme
K7 Methylation
K7 Ubiquitination
S11 Phosphorylation
T15 Phosphorylation
K23 Acetylation
K23 Ubiquitination
K66 Ubiquitination
K92 Sumoylation
K97 Acetylation
K97 Ubiquitination
K118 Ubiquitination
K129 Ubiquitination
Y169 Phosphorylation
S182 Phosphorylation
S193 Phosphorylation
S194 Phosphorylation
S209 Phosphorylation
S216 Phosphorylation
S226 Phosphorylation
T228 Phosphorylation
S250 Phosphorylation
S252 Phosphorylation
S260 Phosphorylation
S262 Phosphorylation
S268 Phosphorylation
S270 Phosphorylation
S277 Phosphorylation
S279 Phosphorylation
S281 Phosphorylation
S292 Phosphorylation
S294 Phosphorylation
S296 Phosphorylation

研究背景

機能:

Involved in pre-mRNA splicing as a component of the spliceosome.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Component of the spliceosome B complex (Probable). Interacts (via N-terminal interaction domain) with ZMAT2 AND MFAP1 (Probable).

タンパク質ファミリー:

Belongs to the PRP38 family.

研究領域

· Genetic Information Processing > Transcription > Spliceosome.

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