RASA3 Antibody - #DF4386

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製品: RASA3 Antibody
カタログ: DF4386
タンパク質の説明: Rabbit polyclonal antibody to RASA3
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Dog, Chicken
分子量: 96 KD; 96kD(Calculated).
ユニプロット: Q14644
RRID: AB_2836741

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(88%), Bovine(88%), Dog(88%), Chicken(88%)
クローナリティ:
Polyclonal
特異性:
RASA3 Antibody detects endogenous levels of total RASA3.
RRID:
AB_2836741
引用形式: Affinity Biosciences Cat# DF4386, RRID:AB_2836741.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein 1 family; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins P4-binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; MGC46517; MGC47588; Ras GTPase activating protein 3; Ras GTPase-activating protein 3; RAS p21 protein activator 3; RASA 3; RASA3; RASA3_HUMAN;

免疫原

免疫原:
Uniprot:

Q14644(RASA3_HUMAN) >>Visit HPA database.

遺伝子(ID):
RASA3(22821)
タンパク質配列:
MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
88
Bovine
88
Dog
88
Chicken
88
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q14644 基板として

Site PTM Type Enzyme
A2 Acetylation
S13 Phosphorylation
K15 Ubiquitination
K32 Ubiquitination
K55 Ubiquitination
Y61 Phosphorylation
Y66 Phosphorylation
S77 Phosphorylation
Y79 Phosphorylation
S90 Phosphorylation
K99 Ubiquitination
K104 Ubiquitination
T110 Phosphorylation
K146 Ubiquitination
Y199 Phosphorylation
T203 Phosphorylation
S207 Phosphorylation
Y208 Phosphorylation
K223 Acetylation
K237 Ubiquitination
K251 Ubiquitination
S257 Phosphorylation
K273 Ubiquitination
K276 Ubiquitination
S282 Phosphorylation
K309 Ubiquitination
Y345 Phosphorylation
K378 Ubiquitination
T450 Phosphorylation
T511 Phosphorylation
T518 Phosphorylation
T521 Phosphorylation
S524 Phosphorylation
S526 Phosphorylation
K527 Acetylation
K527 Ubiquitination
K529 Acetylation
S532 Phosphorylation
K555 Ubiquitination
S562 Phosphorylation
S563 Phosphorylation
S564 Phosphorylation
K570 Ubiquitination
K579 Ubiquitination
K596 Acetylation
K599 Acetylation
K616 Ubiquitination
K634 Ubiquitination
K641 Ubiquitination
K643 Ubiquitination
K674 Ubiquitination
S703 Phosphorylation
K746 Ubiquitination
Y757 Phosphorylation
T776 Phosphorylation
Y777 Phosphorylation
K778 Ubiquitination
K781 Ubiquitination
Y797 Phosphorylation
T805 Phosphorylation
K806 Ubiquitination
Y807 Phosphorylation
S809 Phosphorylation
K817 Ubiquitination
S818 Phosphorylation
Y822 Phosphorylation
S827 Phosphorylation
T829 Phosphorylation
S830 Phosphorylation
T831 Phosphorylation
S833 Phosphorylation

研究背景

機能:

Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

細胞の位置付け:

Cell membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

研究領域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

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