製品: SERPINB4 Antibody
カタログ: DF4491
タンパク質の説明: Rabbit polyclonal antibody to SERPINB4
アプリケーション: WB IF/ICC
反応性: Human
分子量: 45 KD; 45kD(Calculated).
ユニプロット: P48594
RRID: AB_2836842

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
SERPINB4 Antibody detects endogenous levels of total SERPINB4.
RRID:
AB_2836842
引用形式: Affinity Biosciences Cat# DF4491, RRID:AB_2836842.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin); SCCA 2; SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; Serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P48594 SPB4_HUMAN:

Squamous cells.

タンパク質配列:
MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP

PTMs - P48594 基板として

Site PTM Type Enzyme
Y73 Phosphorylation
Y127 Phosphorylation
S130 Phosphorylation
S149 Phosphorylation
S153 Phosphorylation
Y181 Phosphorylation
T347 Phosphorylation
S355 Phosphorylation
S356 Phosphorylation
T359 Phosphorylation
Y384 Phosphorylation

研究背景

機能:

May act as a protease inhibitor to modulate the host immune response against tumor cells.

細胞の位置付け:

Cytoplasm.
Note: Seems to also be secreted in plasma by cancerous cells but at a low level.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Squamous cells.

タンパク質ファミリー:

Belongs to the serpin family. Ov-serpin subfamily.

研究領域

· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.

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