製品: SH3GLB2 Antibody
カタログ: DF4503
タンパク質の説明: Rabbit polyclonal antibody to SH3GLB2
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 48 KD; 44kD(Calculated).
ユニプロット: Q9NR46
RRID: AB_2836854

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 100ul $280 在庫あり
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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(92%)
クローナリティ:
Polyclonal
特異性:
SH3GLB2 Antibody detects endogenous levels of total SH3GLB2.
RRID:
AB_2836854
引用形式: Affinity Biosciences Cat# DF4503, RRID:AB_2836854.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Endophilin B2; Endophilin-B2; OTTHUMP00000022320; PP6569; PP9455; Retinoid receptor induced gene 1; RRIG1; SH3 containing protein SH3GLB2; SH3 domain GRB2 like endophilin B2; SH3 domain-containing GRB2-like protein B2; SH3GLB2; SHLB2_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NR46 SHLB2_HUMAN:

Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.

タンパク質配列:
MDFNMKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTEKILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMADAASELGPTTPYGKTLIKVAEAEKQLGAAERDFIHTASISFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTAAATMPVVPSVASLAPPGEASLCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
92
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NR46 基板として

Site PTM Type Enzyme
M1 Acetylation
K6 Methylation
K7 Methylation
K7 Ubiquitination
S10 Phosphorylation
K26 Ubiquitination
K32 Ubiquitination
K50 Ubiquitination
K55 Ubiquitination
Y77 Phosphorylation
K79 Ubiquitination
T108 Phosphorylation
T109 Phosphorylation
K117 Ubiquitination
K123 Ubiquitination
T142 Phosphorylation
K153 Ubiquitination
K173 Ubiquitination
K178 Acetylation
K180 Acetylation
K185 Acetylation
K185 Ubiquitination
T188 Phosphorylation
T195 Phosphorylation
R198 Methylation
S205 Phosphorylation
S207 Phosphorylation
R230 Methylation
S259 Phosphorylation
T262 Phosphorylation
Y263 Phosphorylation
K276 Ubiquitination
S395 Phosphorylation

研究背景

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.

サブユニット構造:

Homodimer, and heterodimer with SH3GLB1.

タンパク質ファミリー:

Belongs to the endophilin family.

研究領域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

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