SIRPB1 Antibody - #DF4507
製品: | SIRPB1 Antibody |
カタログ: | DF4507 |
タンパク質の説明: | Rabbit polyclonal antibody to SIRPB1 |
アプリケーション: | WB IF/ICC |
反応性: | Human, Rat |
分子量: | 48 KD; 43kD(Calculated). |
ユニプロット: | O00241 |
RRID: | AB_2836858 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4507, RRID:AB_2836858.
折りたたみ/展開
CD172 antigen like family member B; CD172b; CD172b antigen; DKFZp686A05192; Signal regulatory protein beta 1; SIRP BETA 1; SIRP beta 1 isoform 3;
免疫原
- O00241 SIRB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPVPASWPHLPSPFLLMTLLLGRLTGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPLLVALLLGPKLLLVVGVSAIYICWKQKA
PTMs - O00241 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K82 | Ubiquitination | Uniprot | |
K97 | Ubiquitination | Uniprot | |
Y119 | Phosphorylation | Uniprot | |
K182 | Ubiquitination | Uniprot | |
N244 | N-Glycosylation | Uniprot |
研究背景
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
N-glycosylated.
Cell membrane>Single-pass type I membrane protein.
Detected in monocytes and dendritic cells.
Homodimer; disulfide-linked. Interacts with TYROBP. This interaction results in the recruitment of SYK.
研究領域
· Organismal Systems > Development > Osteoclast differentiation. (View pathway)
参考文献
Application: WB Species: Mouse Sample: hippocampus tissue
Application: WB Species: mouse Sample: hippocampal
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