CCT5 Antibody - #DF4559
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4559, RRID:AB_2836910.
折りたたみ／展開
CCT 5; CCT epsilon; CCT5; CCTE; CCTepsilon; Chaperonin containing T-complex polypeptide 1, subunit 5; Chaperonin containing TCP 1 epsilon; Chaperonin containing TCP 1 subunit 5; Chaperonin containing TCP 1 subunit 5 epsilon; Chaperonin containing TCP1 epsilon; Chaperonin containing TCP1 subunit 5; Chaperonin containing TCP1 subunit 5 epsilon; KIAA0098; T complex protein 1 epsilon subunit; T complex protein 1 subunit epsilon; TCP 1 epsilon; TCP1epsilon; TCPE;
免疫原
- P48643 TCPE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P48643 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| Y12 | Phosphorylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| R27 | Methylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| K42 | Sumoylation | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| R49 | Methylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| K59 | Acetylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K64 | Acetylation | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| R132 | Methylation | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| K160 | Acetylation | Uniprot | |
| K160 | Sumoylation | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K176 | Sumoylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| C181 | S-Nitrosylation | Uniprot | |
| K210 | Sumoylation | Uniprot | |
| K210 | Ubiquitination | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| K223 | Acetylation | Uniprot | |
| K223 | Ubiquitination | Uniprot | |
| K226 | Sumoylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K232 | Acetylation | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| K242 | Acetylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| K261 | Acetylation | Uniprot | |
| K261 | Ubiquitination | Uniprot | |
| K263 | Acetylation | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| K265 | Acetylation | Uniprot | |
| K265 | Sumoylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| S270 | Phosphorylation | Uniprot | |
| Y274 | Phosphorylation | Uniprot | |
| K275 | Acetylation | Uniprot | |
| K275 | Ubiquitination | Uniprot | |
| K279 | Acetylation | Uniprot | |
| K279 | Sumoylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K282 | Acetylation | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| S346 | Phosphorylation | Uniprot | |
| K368 | Ubiquitination | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| C377 | S-Nitrosylation | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| K399 | Acetylation | Uniprot | |
| K399 | Ubiquitination | Uniprot | |
| C407 | S-Nitrosylation | Uniprot | |
| K439 | Ubiquitination | Uniprot | |
| S463 | Phosphorylation | Uniprot | |
| S466 | Phosphorylation | Uniprot | |
| T473 | Phosphorylation | Uniprot | |
| K483 | Ubiquitination | Uniprot | |
| K496 | Acetylation | Uniprot | |
| K496 | Ubiquitination | Uniprot | |
| K502 | Sumoylation | Uniprot | |
| K502 | Ubiquitination | Uniprot | |
| T509 | Phosphorylation | Uniprot | |
| K513 | Ubiquitination | Uniprot | |
| K514 | Ubiquitination | Uniprot | |
| S518 | Phosphorylation | Uniprot | |
| T521 | Phosphorylation | Uniprot | |
| K529 | Ubiquitination | Uniprot | |
| R534 | Methylation | Uniprot | |
| K535 | Ubiquitination | Uniprot | |
| S539 | Phosphorylation | Uniprot |
研究背景
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Cytoplasm. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Interacts with DNAAF4 (By similarity).
Belongs to the TCP-1 chaperonin family.
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