製品: EIF2B3 Antibody
カタログ: DF4578
タンパク質の説明: Rabbit polyclonal antibody to EIF2B3
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 50 KD; 50kD(Calculated).
ユニプロット: Q9NR50
RRID: AB_2836942

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(88%), Horse(100%), Sheep(88%), Rabbit(88%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
EIF2B3 Antibody detects endogenous levels of total EIF2B3.
RRID:
AB_2836942
引用形式: Affinity Biosciences Cat# DF4578, RRID:AB_2836942.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EI2BG_HUMAN; EIF 2B; eIF 2B GDP GTP exchange factor subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B-gamma; Eif2b3; EIF2Bgamma; Eukaryotic translation initiation factor 2B subunit 3 gamma; Eukaryotic translation initiation factor 2B, gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; OTTHUMP00000010262; OTTHUMP00000010263; Translation initiation factor eIF-2B subunit gamma;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
88
Sheep
88
Dog
88
Rabbit
88
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NR50 基板として

Site PTM Type Enzyme
M1 Acetylation
K61 Ubiquitination
K68 Ubiquitination
K72 Ubiquitination
Y92 Phosphorylation
K96 Ubiquitination
K134 Methylation
K134 Ubiquitination
K146 Ubiquitination
K148 Methylation
K165 Ubiquitination
K189 Ubiquitination
S220 Phosphorylation
K235 Ubiquitination
K259 Ubiquitination
S260 Phosphorylation
Y264 Phosphorylation
S265 Phosphorylation
K268 Ubiquitination
S314 Phosphorylation
K328 Ubiquitination
K349 Ubiquitination
K367 Ubiquitination
K382 Ubiquitination
K422 Ubiquitination
S428 Phosphorylation

研究背景

機能:

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

サブユニット構造:

Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

タンパク質ファミリー:

Belongs to the eIF-2B gamma/epsilon subunits family.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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