製品: TMBIM1 Antibody
カタログ: DF4580
タンパク質の説明: Rabbit polyclonal antibody to TMBIM1
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Rabbit, Dog, Xenopus
分子量: 35 KD; 35kD(Calculated).
ユニプロット: Q969X1
RRID: AB_2836944

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(88%), Rabbit(100%), Dog(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
TMBIM1 Antibody detects endogenous levels of total TMBIM1.
RRID:
AB_2836944
引用形式: Affinity Biosciences Cat# DF4580, RRID:AB_2836944.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

LFG3; MST100; MSTP100; PP1201; Protein lifeguard 3; Protein RECS1 homolog; RECS1; TMBI1_HUMAN; Tmbim1; Transmembrane BAX inhibitor motif containing 1; Transmembrane BAX inhibitor motif-containing protein 1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Xenopus
100
Rabbit
100
Horse
88
Sheep
75
Chicken
75
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q969X1 基板として

Site PTM Type Enzyme
S2 Phosphorylation
Y67 Phosphorylation
Y73 Phosphorylation
S81 Phosphorylation
S83 Phosphorylation
S127 Phosphorylation

研究背景

機能:

Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.

細胞の位置付け:

Membrane>Multi-pass membrane protein. Lysosome membrane. Endosome membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the BI1 family. LFG subfamily.

参考文献

1). miR‐485's anti‐drug resistant epilepsy effects by regulating SV2A/PSD‐95 and targeting ABCC1 and neuronal signaling‐transduction proteins in hippocampus of rats. Brain and Behavior, 2021 (PubMed: 34291586) [IF=3.1]

Application: WB    Species: Rat    Sample: hippocampus tissue

FIGURE 6 Theexpressionofneuronalsignaling-transduction proteinsinhippocampusofDREratsat9weeksafterSE.(a)Western blottingbands;(b)barographsofexpressionlevels.*p<.05versusthe

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