VTI1A Antibody - #DF4609
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4609, RRID:AB_2836973.
折りたたみ／展開
MMDS3; MVti1; SNARE Vti1a beta protein; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport through interaction with tSNAREs homolog 1A (yeast); Vesicle transport v-SNARE protein Vti1-like 2; Vti1 rp2; Vti1-rp2; Vti1a; VTI1A vesicle transport through interaction with t-SNAREs 1A; VTI1A_HUMAN; VTI1RP2;
免疫原
- Q96AJ9 VTI1A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILMAITFSVRRH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96AJ9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| Y95 | Phosphorylation | Uniprot | |
| S110 | Phosphorylation | Uniprot | |
| T122 | Phosphorylation | Uniprot | |
| Y136 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| S178 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot |
研究背景
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.
Cytoplasmic vesicle. Golgi apparatus membrane>Single-pass type IV membrane protein.
Interacts with distinct SNARE complexes that contain either STX5 or STX6. Interacts with NAPA and, to a lesser extent, with NAPG. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A.
Belongs to the VTI1 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.
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