CACNG1 Antibody - #DF4612
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4612, RRID:AB_2836976.
折りたたみ／展開
CACNG1; CACNLG; CACNLG calcium channel neuronal dihydrpyridine sensitive gamma subunit; Calcium channel L type gamma polypeptide; Calcium channel voltage dependent gamma subunit 1; CCG1_HUMAN; Dihydropyridine sensitive L type skeletal muscle calcium channel gamma subunit; Dihydropyridine sensitive L type skeletal muscle calcium channel subunit gamma; Dihydropyridine-sensitive L-type; fb43f02; fi19g08; L type calcium channel gamma polypeptide; MGC117703; skeletal muscle calcium channel subunit gamma; Voltage dependent calcium channel gamma 1 subunit 2; Voltage-dependent calcium channel gamma-1 subunit; wu:fb43f02; zgc:55364;
免疫原
- Q06432 CCG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q06432 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y135 | Phosphorylation | Uniprot | |
| S161 | Phosphorylation | Uniprot |
研究背景
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
N-glycosylated.
Cell membrane>Sarcolemma>Multi-pass membrane protein.
Skeletal muscle.
Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
研究領域
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
· Human Diseases > Cardiovascular diseases > Hypertrophic cardiomyopathy (HCM).
· Human Diseases > Cardiovascular diseases > Arrhythmogenic right ventricular cardiomyopathy (ARVC).
· Human Diseases > Cardiovascular diseases > Dilated cardiomyopathy (DCM).
· Organismal Systems > Circulatory system > Cardiac muscle contraction. (View pathway)
· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes. (View pathway)
· Organismal Systems > Endocrine system > Oxytocin signaling pathway.
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