製品: TBPL2 Antibody
カタログ: DF4661
タンパク質の説明: Rabbit polyclonal antibody to TBPL2
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Dog
分子量: 41 KD; 42kD(Calculated).
ユニプロット: Q6SJ96
RRID: AB_2837012

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Dog(89%)
クローナリティ:
Polyclonal
特異性:
TBPL2 Antibody detects endogenous levels of total TBPL2.
RRID:
AB_2837012
引用形式: Affinity Biosciences Cat# DF4661, RRID:AB_2837012.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

TATA binding protein 2; TATA box binding protein like 2; TATA box-binding protein-like 2; TATA box-binding protein-like protein 2; TATA box-binding protein-related factor 3; TATA-binding protein 2; TBP related factor 3; TBP-like protein 2; TBP-related factor 3; Tbpl2; TBPL2_HUMAN; TRF3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q6SJ96 TBPL2_HUMAN:

Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.

タンパク質配列:
MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
89
Pig
78
Bovine
78
Sheep
78
Rabbit
78
Xenopus
56
Chicken
56
Horse
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6SJ96 基板として

Site PTM Type Enzyme
K262 Ubiquitination
S267 Phosphorylation
Y274 Phosphorylation
S344 Phosphorylation

研究背景

機能:

Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).

細胞の位置付け:

Cytoplasm. Nucleus.
Note: Present in the cytoplasm during cytokinesis.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.

サブユニット構造:

Interacts with TAF3.

タンパク質ファミリー:

Belongs to the TBP family.

研究領域

· Genetic Information Processing > Transcription > Basal transcription factors.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.

· Human Diseases > Cancers: Overview > Viral carcinogenesis.

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For Research Use Only.
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