IL13RA2 Antibody - #DF4706
| 製品: | IL13RA2 Antibody |
| カタログ: | DF4706 |
| タンパク質の説明: | Rabbit polyclonal antibody to IL13RA2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 50 KD; 44kD(Calculated). |
| ユニプロット: | Q14627 |
| RRID: | AB_2837057 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4706, RRID:AB_2837057.
折りたたみ／展開
Cancer/testis antigen 19; CD213a2; CT19; I13R2_HUMAN; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; IL13 receptor; IL13BP; IL13R; Il13ra2; Interleukin 13 binding protein; Interleukin 13 receptor alpha 2 chain; Interleukin-13 receptor subunit alpha-2; Interleukin-13-binding protein;
免疫原
- Q14627 I13R2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT
PTMs - Q14627 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N215 | N-Glycosylation | Uniprot |
研究背景
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Membrane>Single-pass type I membrane protein.
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Belongs to the type I cytokine receptor family. Type 5 subfamily.
研究領域
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
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