IL18BP Antibody - #DF4709
| 製品: | IL18BP Antibody |
| カタログ: | DF4709 |
| タンパク質の説明: | Rabbit polyclonal antibody to IL18BP |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 分子量: | 44 KD; 21kD(Calculated). |
| ユニプロット: | O95998 |
| RRID: | AB_2837060 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4709, RRID:AB_2837060.
折りたたみ／展開
I18BP_HUMAN; IL-18BP; IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Interleukin-18-binding protein; MC51L 53L 54L homolog gene product; Tadekinig alfa; Tadekinig-alfa;
免疫原
A synthesized peptide derived from human IL18BP, corresponding to a region within C-terminal amino acids.
- O95998 I18BP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTMRHNWTPDLSPLWVLLLCAHVVTLLVRATPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQEALPSSHSSPQQQG
PTMs - O95998 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T31 | Phosphorylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| S46 | O-Glycosylation | Uniprot | |
| T47 | O-Glycosylation | Uniprot | |
| S53 | O-Glycosylation | Uniprot | |
| N103 | N-Glycosylation | Uniprot | |
| N147 | N-Glycosylation | Uniprot |
研究背景
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); N-glycan at Asn-147: dHex1Hex5HexNAc4.
Secreted.
Strongly expressed in heart, lung, placenta and spleen.
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