TBXAS1 Antibody - #DF4746

(1)  
製品: TBXAS1 Antibody
カタログ: DF4746
タンパク質の説明: Rabbit polyclonal antibody to TBXAS1
アプリケーション: WB IF/ICC
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 61kD; 61kD(Calculated).
ユニプロット: P24557
RRID: AB_2837097

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Rabbit(100%), Dog(100%), Chicken(88%), Xenopus(88%)
クローナリティ:
Polyclonal
特異性:
TBXAS1 Antibody detects endogenous levels of total TBXAS1.
RRID:
AB_2837097
引用形式: Affinity Biosciences Cat# DF4746, RRID:AB_2837097.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450, family 5, subfamily A, polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; Tbxas1; THAS; THAS_HUMAN; Thromboxane A synthase 1 (platelet); Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A); Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS;

免疫原

免疫原:
Uniprot:

P24557(THAS_HUMAN) >>Visit HPA database.

遺伝子(ID):
TBXAS1(6916)
発現特異性:
P24557 THAS_HUMAN:

Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.

タンパク質配列:
MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
100
Pig
88
Horse
88
Bovine
88
Sheep
88
Xenopus
88
Chicken
88
Zebrafish
75
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P24557 基板として

Site PTM Type Enzyme
T57 Phosphorylation

研究背景

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.

サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the cytochrome P450 family.

研究領域

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Immune system > Platelet activation.   (View pathway)

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