製品: ATG16L2 Antibody
カタログ: DF4817
タンパク質の説明: Rabbit polyclonal antibody to ATG16L2
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Bovine, Sheep, Rabbit
分子量: 69 KD; 69kD(Calculated).
ユニプロット: Q8NAA4
RRID: AB_2837168

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(82%), Sheep(82%), Rabbit(91%)
クローナリティ:
Polyclonal
特異性:
ATG16L2 Antibody detects endogenous levels of total ATG16L2.
RRID:
AB_2837168
引用形式: Affinity Biosciences Cat# DF4817, RRID:AB_2837168.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

A16L2_HUMAN; APG16-like 2; ATG16 autophagy related 16-like 2; ATG16B; Atg16l2; autophagy related 16-like 2 (S. cerevisiae); Autophagy-related protein 16-2; WD repeat-containing protein 80; WDR80;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
91
Bovine
82
Sheep
82
Pig
73
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8NAA4 基板として

Site PTM Type Enzyme
T232 Phosphorylation
S234 Phosphorylation
S236 Phosphorylation
T241 Phosphorylation
S278 Phosphorylation
S304 Phosphorylation
S441 Phosphorylation
T552 Phosphorylation
S557 Phosphorylation
S608 Phosphorylation

研究背景

機能:

May play a role in autophagy.

細胞の位置付け:

Cytoplasm.
Note: Localizes also to discrete punctae along the ciliary axoneme.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the WD repeat ATG16 family.

研究領域

· Cellular Processes > Transport and catabolism > Autophagy - animal.   (View pathway)

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