DSG1 Antibody - #DF4821
| 製品: | DSG1 Antibody |
| カタログ: | DF4821 |
| タンパク質の説明: | Rabbit polyclonal antibody to DSG1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 114 KD; 114kD(Calculated). |
| ユニプロット: | Q02413 |
| RRID: | AB_2837186 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4821, RRID:AB_2837186.
折りたたみ／展開
Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DGI; DSG; DSG1; DSG1_HUMAN; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1;
免疫原
- Q02413 DSG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQYSK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02413 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S23 | Phosphorylation | Uniprot | |
| Y32 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| S43 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| C77 | S-Nitrosylation | Uniprot | |
| N110 | N-Glycosylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| T215 | Phosphorylation | Uniprot | |
| T220 | Phosphorylation | Uniprot | |
| S437 | Phosphorylation | Uniprot | |
| K450 | Acetylation | Uniprot | |
| Y515 | Phosphorylation | Uniprot | |
| T519 | Phosphorylation | Uniprot | |
| T520 | Phosphorylation | Uniprot | |
| S579 | Phosphorylation | Uniprot | |
| S630 | Phosphorylation | Uniprot | |
| Y633 | Phosphorylation | Uniprot | |
| T634 | Phosphorylation | Uniprot | |
| Y637 | Phosphorylation | Uniprot | |
| T652 | Phosphorylation | Uniprot | |
| Y672 | Phosphorylation | Uniprot | |
| Y1042 | Phosphorylation | Uniprot | |
| S1043 | Phosphorylation | Uniprot | |
| T1044 | Phosphorylation | Uniprot |
研究背景
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Cell membrane>Single-pass type I membrane protein. Cell junction>Desmosome.
Epidermis, tongue, tonsil and esophagus.
Binds to JUP/plakoglobin.
(Microbial infection) Interacts with Staphylococcus aureus protein SdrD; this interaction increases S. aureus adherence to keratinocytes.
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
研究領域
· Human Diseases > Infectious diseases: Bacterial > Staphylococcus aureus infection.
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