製品: Carboxypeptidase A Antibody
カタログ: DF4829
タンパク質の説明: Rabbit polyclonal antibody to Carboxypeptidase A
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Dog
分子量: 47 KD; 47kD(Calculated).
ユニプロット: P15085
RRID: AB_2837194

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Dog(89%)
クローナリティ:
Polyclonal
特異性:
Carboxypeptidase A Antibody detects endogenous levels of total Carboxypeptidase A.
RRID:
AB_2837194
引用形式: Affinity Biosciences Cat# DF4829, RRID:AB_2837194.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

carboxypeptidase A1 (pancreatic); Carboxypeptidase A1; Carboxypeptidase A1 precursor; CBPA1_HUMAN; CPA; CPA1; Pancreatic carboxypeptidase A1; Procarboxypeptidase A1 pancreatic;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
89
Pig
75
Chicken
60
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P15085 基板として

Site PTM Type Enzyme
Y152 Phosphorylation
Y158 Phosphorylation
S272 Phosphorylation
T274 Phosphorylation
T338 Phosphorylation
Y344 Phosphorylation
T346 Phosphorylation
S352 Phosphorylation

研究背景

機能:

Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Monomer. May form a complex with proelastase 2.

タンパク質ファミリー:

Belongs to the peptidase M14 family.

研究領域

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Protein digestion and absorption.

Restrictive clause

 

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