EDG5 Antibody - #DF4921
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4921, RRID:AB_2837274.
折りたたみ／展開
AGR16; EDG 5; EDG5; Endothelial Cell Differentiation Gene 5; Endothelial differentiation G protein coupled receptor 5; Endothelial differentiation G-protein coupled receptor 5; Endothelial differentiation sphingolipid G protein coupled receptor 5; Gpcr13; H218; LPb2; Lysophospholipid receptor B2; S1P receptor 2; S1P receptor Edg 5; S1P receptor Edg-5; S1P receptor EDG5; S1P2; S1pr2; S1PR2_HUMAN; Sphingosine 1 phosphate receptor Edg 5; Sphingosine 1-phosphate receptor 2; Sphingosine 1-phosphate receptor Edg-5;
免疫原
- O95136 S1PR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95136 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S142 | Phosphorylation | Uniprot | |
| K144 | Acetylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot |
研究背景
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).
Cell membrane>Multi-pass membrane protein.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
Restrictive clause
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