製品: TAS2R13 Antibody
カタログ: DF5158
タンパク質の説明: Rabbit polyclonal antibody to TAS2R13
アプリケーション: WB IF/ICC
反応性: Human
分子量: 35 KD; 35kD(Calculated).
ユニプロット: Q9NYV9
RRID: AB_2837348

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
TAS2R13 Antibody detects endogenous levels of total TAS2R13.
RRID:
AB_2837348
引用形式: Affinity Biosciences Cat# DF5158, RRID:AB_2837348.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

T2R13; T2R13_HUMAN; Tas2r13; Taste receptor family B member 3; Taste receptor type 2 member 13; Taste receptor, family B, member 3; Taste receptor, type 2, member 13; TRB3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NYV9 T2R13_HUMAN:

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

タンパク質配列:
MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIILAISRIGLIWEILVSWFLALHYLAIFVSGTGLRIMIFSWIVSNHFNLWLATIFSIFYLLKIASFSSPAFLYLKWRVNKVILMILLGTLVFLFLNLIQINMHIKDWLDRYERNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHRDPRTKVHTNALKIVISFLLFYASFFLCVLISWISELYQNTVIYMLCETIGVFSPSSHSFLLILGNAKLRQAFLLVAAKVWAKR

PTMs - Q9NYV9 基板として

Site PTM Type Enzyme
S54 Phosphorylation

研究背景

機能:

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor T2R family.

研究領域

· Organismal Systems > Sensory system > Taste transduction.

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