製品: OR1D2 Antibody
カタログ: DF5061
タンパク質の説明: Rabbit polyclonal antibody to OR1D2
アプリケーション: WB IF/ICC
反応性: Human
分子量: 40 KD; 35kD(Calculated).
ユニプロット: P34982
RRID: AB_2837420

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
OR1D2 Antibody detects endogenous levels of total OR1D2.
RRID:
AB_2837420
引用形式: Affinity Biosciences Cat# DF5061, RRID:AB_2837420.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Olfactory receptor 17-4; Olfactory receptor 1D2; Olfactory receptor like protein HGMP07E; Olfactory receptor OR17-6; Olfactory receptor, family 1, subfamily D, member 2; Olfactory receptor-like protein HGMP07E; OLFR1; OR17-4; OR1D2; OR1D2_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P34982 OR1D2_HUMAN:

Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium.

タンパク質配列:
MDGGNQSEGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRLHTPVYFFLANLSFTDLFFVTNTIPKMLVNLQSHNKAISYAGCLTQLYFLVSLVALDNLILAVMAYDRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCEMYVLLRMACSNIQINHTVLIATGCFIFLIPFGFVIISYVLIIRAILRIPSVSKKYKAFSTCASHLGAVSLFYGTLCMVYLKPLHTYSVKDSVATVMYAVVTPMMNPFIYSLRNKDMHGALGRLLDKHFKRLT

PTMs - P34982 基板として

Site PTM Type Enzyme
Y123 Phosphorylation
Y218 Phosphorylation

研究背景

機能:

Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.
Note: In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

研究領域

· Organismal Systems > Sensory system > Olfactory transduction.

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